Dose-equivalence by class

Statin dose equivalents and «Affordable Medicines» reimbursement

Atorvastatin 20 mg ≈ rosuvastatin 10 mg at equal LDL-C lowering (modeled estimate). This page shows the equivalent dose for each statin alongside its current status in Ukraine's «Affordable Medicines» (Dostupni Liky) reimbursement register — the only source that combines these two facts with visible citations.

Statin equivalence + reimbursement table

Equivalent dose column: each statin's dose modeled to lower LDL-C as much as atorvastatin 20 mg/day, by a sourced log-linear model. «—» means the engine cannot reach that LDL-C lowering within the licensed dose range; «†» marks a licensed-minimum dose that slightly over-treats; «‡» uses VOYAGER individual-patient data — the stronger basis for atorvastatin, rosuvastatin and simvastatin. Reimbursement column: from Ukraine's open-data «Доступні ліки» register (MOZ); fail-closed — a positive claim is only made when the dataset is current. Educational estimate, not a prescription.
Drug≈ Equivalent to atorvastatin 20 mg«Affordable Medicines»?Reimbursed tablet strengths
Atorvastatin20 mgNot confirmed
Rosuvastatin10 mgNot confirmed
Simvastatin80 mg10 mg, 20 mg, 40 mg
Pravastatin80 mgNot confirmed
Lovastatin63.5 mgNot confirmed
Fluvastatin80 mgNot confirmed
Pitavastatin4 mgNot confirmed

‡ a dose capped at that statin's licensed maximum — it does not fully reach the reference row's LDL-C lowering (under-treats). Individual LDL-C response varies by roughly ±15 percentage points (VOYAGER).

Sources and evidence

Equivalence estimates: from a sourced log-linear dose-response model (Law et al. 2003 and VOYAGER IPD meta-analysis). See the formula and its verbatim source quote in Methods

Reimbursement data: Ukraine's «Affordable Medicines» open-data register (MOZ order № 1409, August 2025). Open-data source (data.gov.ua)

Open the interactive equivalent-dose tool

Data current as of June 2026.

Educational PK model: not clinical guidance. Confirm any dose change with a prescriber or pharmacist.