Dose-equivalence by class
Antipsychotic equivalent doses
Antipsychotic equivalent doses express each drug — for example olanzapine and risperidone — as an olanzapine-equivalent using the published Classical Mean Dose method; there is no gold-standard conversion, so this is an educational population estimate, not a prescription.
Reference table
Each drug expressed as the dose equivalent to olanzapine 10 mg/day, by the published Classical Mean Dose method. No gold standard; population estimate, not a prescription.
| Drug | Equivalent dose |
|---|---|
| Olanzapine | 10 mg |
| Risperidone | 3.8 mg |
| Haloperidol | 7.4 mg |
| Chlorpromazine | 388.8 mg |
| Quetiapine | 322.7 mg |
| Aripiprazole | 14.1 mg |
| Ziprasidone | 79.2 mg |
| Amisulpride | 383.3 mg |
| Clozapine | 306.2 mg |
| Sertindole | 10.8 mg |
| Asenapine | 8.9 mg |
| Zotepine | 132.4 mg |
Common switches
Olanzapine to Risperidone
Olanzapine 10 mg maps to about 3.8 mg of Risperidone (modeled estimate, educational — not a prescription).
Risperidone to Haloperidol
Risperidone 2 mg maps to about 3.9 mg of Haloperidol (modeled estimate, educational — not a prescription).
Educational PK model: not clinical guidance. Confirm any dose change with a prescriber or pharmacist.