Dose-equivalence by class

Statin equivalent doses

Statin equivalent doses are doses of different statins — for example atorvastatin and rosuvastatin — modeled to lower LDL-C by the same percentage; this is an educational estimate from a sourced log-linear dose-response model, and switching between statins can under-dose the target, so it is not a prescription.

Reference table

Doses modeled to lower LDL-C as much as atorvastatin 20 mg, from a sourced log-linear model. Model-interpolated grid; individual LDL-C response varies by roughly ±15 percentage points (VOYAGER), and switching between statins can under-dose the target. Educational estimate, not a prescription.

DrugEquivalent dose
Atorvastatin20 mg
Rosuvastatin10 mg
Simvastatin40 mg
Pravastatin80 mg
Lovastatin63.5 mg
Fluvastatin80 mg
Pitavastatin4 mg

Common switches

Atorvastatin to Rosuvastatin

Atorvastatin 20 mg maps to about 10 mg of Rosuvastatin (modeled estimate, educational — not a prescription).

Simvastatin to Atorvastatin

Simvastatin 40 mg maps to about 10 mg of Atorvastatin (modeled estimate, educational — not a prescription).

Simvastatin to Rosuvastatin

Simvastatin 40 mg maps to about 5 mg of Rosuvastatin (modeled estimate, educational — not a prescription).

Open the interactive equivalent-dose tool

See the formula and its verbatim source quote in Methods

Educational PK model: not clinical guidance. Confirm any dose change with a prescriber or pharmacist.