Dose-equivalence by class

Statin equivalent doses: calculator and table

Equivalent doses

Doses of the other statins modelled to give the same LDL-C reduction as Rosuvastatin 10 mg/day (≈ 43%).

  • 20mg/dayrange 10–80 mg/day
  • 89.8mg/day
  • 254mg/day
  • 63.5mg/dayrange 14.1–80 mg/day
  • 254mg/day
  • 4mg/dayrange 1–4 mg/day

Sources (15)

Original

Oni-Orisan A, et al. (2018) (opens in a new tab) Characterization of Statin LDL-C Dose-response Utilizing Electronic Health Records in a Large Population-based Cohort. Circ Genom Precis Med.

Supporting

Law MR, Wald NJ, Rudnicka AR (2003) (opens in a new tab) Quantifying effect of statins on low density lipoprotein cholesterol, ischaemic heart disease, and stroke: systematic review and meta-analysis. BMJ.

Supporting

Karlson BW, Wiklund O, Palmer MK, Nicholls SJ, Lundman P, Barter PJ (2016) (opens in a new tab) Variability of low-density lipoprotein cholesterol response with different doses of atorvastatin, rosuvastatin, and simvastatin: results from VOYAGER. Eur Heart J Cardiovasc Pharmacother.

Supporting

Pfizer (FDA prescribing information) (2024) (opens in a new tab) LIPITOR (atorvastatin calcium) tablets — Dosage and Administration. DailyMed / FDA label.

Supporting

AstraZeneca (FDA prescribing information) (2023) (opens in a new tab) CRESTOR (rosuvastatin) tablets — Dosage and Administration. DailyMed / FDA label.

Supporting

Merck (FDA prescribing information) (2023) (opens in a new tab) ZOCOR (simvastatin) tablets — Dosage and Administration. DailyMed / FDA label.

Supporting

Bristol-Myers Squibb (FDA prescribing information) (2023) (opens in a new tab) PRAVASTATIN SODIUM tablets — Dosage and Administration. DailyMed / FDA label.

Supporting

Merck / generic (FDA prescribing information) (2023) (opens in a new tab) LOVASTATIN tablets — Dosage and Administration. DailyMed / FDA label.

Supporting

Novartis / Sandoz (FDA prescribing information) (2023) (opens in a new tab) LESCOL XL (fluvastatin sodium) extended-release tablets — Dosage and Administration. DailyMed / FDA label.

Supporting

Kowa (FDA prescribing information) (2024) (opens in a new tab) LIVALO (pitavastatin) tablets — Dosage and Administration. DailyMed / FDA label.

Supporting

Bristol-Myers Squibb (FDA prescribing information) (2023) (opens in a new tab) PRAVASTATIN SODIUM tablets — Dosage and Administration. DailyMed / FDA label.

Supporting

Novartis / Sandoz (FDA prescribing information) (2023) (opens in a new tab) LESCOL (fluvastatin sodium) capsules — Description and Dosage. DailyMed / FDA label.

Supporting

Vo NX, Pham HL, Bui TT, Bui TT (2024) (opens in a new tab) Systematic Review on Efficacy, Effectiveness, and Safety of Pitavastatin in Dyslipidemia in Asia. Healthcare.

Supporting

Karlson BW, Palmer MK, Nicholls SJ, Lundman P, Barter PJ (2016) (opens in a new tab) Doses of rosuvastatin, atorvastatin and simvastatin that induce equal reductions in LDL-C and non-HDL-C: results from the VOYAGER meta-analysis. Eur J Prev Cardiol.

Supporting

Grundy SM, Stone NJ, Bailey AL, et al. (2019) (opens in a new tab) 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol. Circulation.

Method reviewpending

Data current as of July 2026.

Educational PK model: not clinical guidance. Confirm any dose change with a prescriber or pharmacist.