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Find an equivalent dose
Estimate an equivalent dose when switching between drugs in the same class. Results are modeled estimates from the parameters you entered.
Statin dose equivalence
Currently takingSwitching to
at
Modeled equivalent dose
about20mg/day
Range 10–80 mg/day — Most patients fall within this range; an individual may differ.
Evidence: Tier B — Reasonable method with moderate or indirect supporting evidence.
20 mg
10
20
40
80
Atorvastatin · equivalent likely range
Rosuvastatin 10 mg/day ≈ Atorvastatin 20 mg/day at an equal LDL-C reduction (~43%).
Why this estimate & cautions
Cross-statin noteThis cross-statin estimate uses the Law equal-LDL anchor table. Individual-patient (VOYAGER) data give a higher potency ratio (rosuvastatin is about 3–3.5× atorvastatin and about 7–8× simvastatin), so this may under-dose the target — verify against the patient's achieved LDL-C.
Population-average equivalence on a surrogate endpoint (LDL-C reduction), not cardiovascular outcomes; an individual patient may fall outside the displayed band. Equipotent dose, not interchangeable product.
Educational PK model — not clinical guidance. Confirm any dose change with a prescriber or pharmacist.