Antidepressant equivalent doses
Antidepressant equivalent doses express each drug — for example citalopram, sertraline and fluoxetine — as a fluoxetine-equivalent daily dose from peer-reviewed averages for acute depression; it is an educational population estimate, not a tapering or withdrawal guide and not a prescription.
Reference table
Each drug expressed as the dose equivalent to fluoxetine 20 mg/day, from peer-reviewed averages for acute depression. Population estimate, not a tapering guide. Educational, not a prescription.
| Drug | Equivalent dose |
|---|---|
| Fluoxetine | 20 mg |
| Citalopram | 20 mg |
| Sertraline | 49.3 mg |
| Escitalopram | 9 mg |
| Paroxetine | 17 mg |
| Fluvoxamine | 71.7 mg |
| Venlafaxine | 74.7 mg |
| Mirtazapine | 25.5 mg |
| Amitriptyline | 61.2 mg |
| Clomipramine | 58.1 mg |
| Nortriptyline | 50.5 mg |
Common switches
Citalopram to Sertraline
Citalopram 30 mg maps to about 73.9 mg of Sertraline (modeled estimate, educational — not a prescription).
Fluoxetine to Sertraline
Fluoxetine 30 mg maps to about 73.9 mg of Sertraline (modeled estimate, educational — not a prescription).
Citalopram to Escitalopram
Citalopram 30 mg maps to about 13.5 mg of Escitalopram (modeled estimate, educational — not a prescription).